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International Journal of Zoology and Applied Biosciences Research Article
Utilizing human breast tissue biomarkers for accurate breast cancer screening
Vigneshkumar Mani, Saravanan M, Kiran Kumar S, Karthick K, Pradeepa AK
Year : 2025 | Pages: 608-612
Received on: 27/09/2025
Revised on: 28/10/2025
Accepted on: 30/11/2025
Published on: 01/12/2025
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Vigneshkumar Mani, Saravanan M, Kiran Kumar S, Karthick K, Pradeepa AK( 2025).
Utilizing human breast tissue biomarkers for accurate breast cancer screening
. International Journal of Zoology and Applied Biosciences, 10( 6), 608-612.
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Abstract
Breast cancer remains one of the leading causes of morbidity and mortality among women worldwide, emphasizing the need for highly accurate and early diagnostic strategies. Traditional screening techniques such as mammography and ultrasound often face limitations related to sensitivity, specificity, and variability across patient populations. In recent years, human breast tissue biomarkers have emerged as powerful molecular indicators capable of improving the precision of breast cancer screening. This paper presents an analytical overview of biomarker-based screening approaches, focusing on protein, genomic, and epigenetic indicators derived directly from breast tissue. The study highlights key biomarkers such as HER2, BRCA1/2, Ki-67, ER, PR, and epigenetic signatures associated with tumor progression. Additionally, the work emphasizes the clinical relevance, diagnostic accuracy, and translational potential of these biomarkers in early cancer detection. Overall, the integration of tissue-based biomarkers into clinical workflows offers a more reliable, personalized, and sensitive screening alternative, potentially transforming early detection and patient outcomes.
Keywords
Breast cancer screening, Human breast tissue biomarkers, HER2, BRCA1, BRCA2.
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© The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
