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International Journal of Zoology and Applied Biosciences Research Article
Transferosomes: An advanced approach for enhanced transdermal drug delivery
Nodagala Hemalatha, Julisha Malla and Bhavani Ummuri
Year : 2025 | Pages: 697-704
Received on: 10/10/2025
Revised on: 27/10/2025
Accepted on: 23/11/2025
Published on: 01/12/2025
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Nodagala Hemalatha, Julisha Malla and Bhavani Ummuri( 2025).
Transferosomes: An advanced approach for enhanced transdermal drug delivery
. International Journal of Zoology and Applied Biosciences, 10( 6), 697-704.
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Abstract
Transferosomes are an artificial vesicles that can be used for controlled and possibly targeted medication delivery. They are a patented drug delivery technique. Recently, transferosomes were developed, which can deliver both high- and low-molecular-weight medications. This has been used to increase the effectiveness of material transfer across intact skin. Some potential benefits include avoiding first pass metabolism, predicting and extending the duration of activity, minimising unfavourable side effects, using drugs with short half-lives, and improving physiological and pharmacological response. Edge activators and phospholipids are parts of the transferosome's composition. Transferosomes can enter cells directly or through other cells, creating an "osmotic gradient" in the process. Transferosomes are classified similarly to other vesicles including liposomes, niosomes, and micelles. Transferosomes are also find to have applications in animals in transdermal delivery, anti inflammatory and anti arthritic treatment, anti cancer drug delivery etc.The current review discusses transferosome characteristics, preparation techniques, and mechanisms of action.
Keywords
Transferosomes, Targeted drug delivery, Controlled drug delivery, Osmotic gradient, Tran-cellular route.
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© The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
