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International Journal of Zoology and Applied Biosciences Research Article
Proteomics: An emerging tool for molecular understanding and applied biosciences
Sridevi Ranjitha K, Sai Deepika L, Vasanthi M, Yerni Kumari Endra, Naga Jayasree Grandhi, Devika Teku and E L Lakshmi Vani Sruthi Adari
Year : 2025 | Pages: 370-376
Received on: 10/09/2025
Revised on: 22/10/2025
Accepted on: 15/11/2025
Published on: 30/11/2025
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Sridevi Ranjitha K, Sai Deepika L, Vasanthi M, Yerni Kumari Endra, Naga Jayasree Grandhi, Devika Teku and E L Lakshmi Vani Sruthi Adari( 2025).
Proteomics: An emerging tool for molecular understanding and applied biosciences
. International Journal of Zoology and Applied Biosciences, 10( 6), 370-376.
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Abstract
Proteomics makes it possible to comprehend the complete protein complement of a cell, tissue, or organism under carefully regulated conditions, including its composition, structure, function, and connections. Stress or pharmacological side effects can change the pattern of a protein, causing it to either be present or absent or to fluctuate slowly in quantity. Numerous biological fields, including as industry, pharmaceuticals, food microbiology, medicine, and drug discovery, use proteomics.The identification of biomarkers, monitoring of drug effects on patients, and in-vitro and in-vivo proteome analysis of drug-treated individuals demonstrate the close relationship between proteomics advancements and applications and drug development. A snapshot of cellular activity and physiological processes can be obtained from changes in the proteome. Exploring the degree to which the environment, transcriptome, and genome impact the variability of the proteome under particular conditions across time has been made possible by the collecting of quantitative multi-layered omics data on different individuals over predetermined time intervals. Large, repeatable datasets are produced by contemporary quantitative, highly parallel, targeted proteomic techniques, which have unrealized promise for the identification, validation, and discovery of biomarkers.This review's goal is to provide an overview of the developments in targeted proteomics techniques for measuring the cellular proteome and discuss how to use this information to enhance the techniques now employed for precision medicine and biomarker evaluation.
Keywords
Industry, Pharmaceuticals, Food microbiology, Medicine, Drug discovery.
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© The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
