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International Journal of Zoology and Applied Biosciences Research Article

Phytochemical, GC-MS analysis and antibacterial activity of leaf extract of Solanum trilobatum l

Ayyappan M and Saraswathi S

Year : 2025 | Volume: 10 | Issue: 3 | Pages: 113-118

doi: https://doi.org/10.55126/ijzab.2025.v10.i03.015

Received on: 27/04/2025

Revised on: 05/05/2025

Accepted on: 12/05/2025

Published on: 31/05/2025

  • Ayyappan M and Saraswathi S ( 2025).

    Phytochemical, GC-MS analysis and antibacterial activity of leaf extract of Solanum trilobatum l

    . International Journal of Zoology and Applied Biosciences, 10( 3), 113-118.

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Abstract

The study objective was to use GC-MS analysis to extract the phytochemical components from Solanum trilobatum leaves. For phytochemical investigation, S. trilobatum leaves were evaluated for possible antibacterial action against Bacillus subtilis and Staphylococcus aureus. The ethanolic leaf extract of S. trilobatum included 30 distinct phytochemical components, according to the results of the GC-MS analysis. The major phytoconstituents were n-Hexadecanoic acid (14.07), 1-(2-methylsulfanyl-ethyl)-2,8,9-trioxa (12.12), 9,12,15-Octadecatrienoic acid, (Z, Z, Z)- (11.97), Pregn-5-en-3-ol, 20-methyl-21-[3-methyl- (11.88) and Phytol (10.04). Using the disc diffusion technique, the plant extracts were made in ethanolic extracts to test their antibacterial efficacy against B. subtilis and S. aureus bacterial pathogens. Staphylococcus aureus had the highest zone of inhibition and the greatest activity among the S. trilobatum leves employed for antibacterial study. Therefore, the plant's medicinal properties may be due to the presence of these phytochemicals.

Keywords

GC-MS chromatogram, Leaves sample, Phytochemicals, Mass spectrum, S. trilobatum L.

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    © The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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