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International Journal of Zoology and Applied Biosciences Review Article
Pain management in endodontic dentistry: An elaborative review
Ajay Raaj R, Shobana Krishnakumar, Abishek T and Vijay Venkatesh K
Year : 2026 | Volume: 11 | Issue: 1 | Pages: 147-151
Received on: 27/10/2025
Revised on: 29/11/2025
Accepted on: 23/12/2025
Published on: 01/01/2026
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Ajay Raaj R, Shobana Krishnakumar, Abishek T and Vijay Venkatesh K( 2026).
Pain management in endodontic dentistry: An elaborative review
. International Journal of Zoology and Applied Biosciences, 11( 1), 147-151.
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Abstract
This review seeks to provide a thorough overview of the latest advances regarding pharmacological, non-pharmacological, and alternative methods of management of pain in endodontics, while considering their applications in practice and future implications. We synthesized the relevant literature via scientific databases and Chapter texts on mechanisms, pharmacological control, adjunctive clinical methods, psychological contributions, and new therapeutic methods. Local anaesthesia is central to intraoperative pain control but less effective in symptomatic irreversible pulpitis. NSAIDs and corticosteroids remain the most effective systemic options for postoperative pain, especially in multimodal regimens. Intracanal medicaments and non-pharmacological methods such as occlusal reduction, cryotherapy, and laser therapy provide adjunctive benefits. Psychological factors like anxiety and pain anticipation also influence outcomes, while future research is focusing on novel drugs, regenerative approaches, and biomarker-based personalized strategies. For effective pain management in endodontics, a multifaceted and patient-centered approach that includes pharmacological agents, clinical adjunctive methods, and behavioural methods is necessary. Emerging biologically-based and technology-based therapies will continue to be avenues for future improvement of pain control and patient comfort.
Keywords
Endodontic pain, Pain management, Psychological factors, Cryotherapy, Laser therapy.
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© The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
