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International Journal of Zoology and Applied Biosciences Research Article
MTT-Based investigation of cissus quadrangularis effects on human cervical cancer cells
Ramesh M, Subha SC, Vijai Krishna V, Madhumitha N and Linisha N M
Year : 2025 | Pages: 567-570
Received on: 27/09/2025
Revised on: 24/10/2025
Accepted on: 26/11/2025
Published on: 01/12/2025
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Ramesh M, Subha SC, Vijai Krishna V, Madhumitha N and Linisha N M( 2025).
MTT-Based investigation of cissus quadrangularis effects on human cervical cancer cells
. International Journal of Zoology and Applied Biosciences, 10( 6), 567-570.
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Abstract
Cervical cancer remains a leading cause of cancer-related mortality among women worldwide. Natural plant extracts have emerged as promising sources of anticancer agents due to their bioactive compounds and low toxicity. This study investigates the cytotoxic effects of Cissus quadrangularis on the HeLa cell line using the MTT assay. Various concentrations of the plant extract were tested to evaluate cell viability and determine its potential anticancer activity. Results demonstrated a dose-dependent reduction in HeLa cell viability, suggesting significant cytotoxic potential of Cissus quadrangularis. These findings provide preliminary evidence supporting the use of this plant extract as a complementary therapeutic approach for cervical cancer, warranting further in-depth molecular studies.
Keywords
Cissus quadrangularis, HeLa cell line, Cervical cancer, MTT assay, Cytotoxicity.
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© The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
