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International Journal of Zoology and Applied Biosciences Research Article

Immunological and molecular tools for the diagnosis in periodontics

Andal Priyadarshini A, Lochini Suriyanarayanan, Ravi Shankar P L, Sudharsana V

Year : 2025 | Volume: 11 | Issue: 1 | Pages: 180-185

doi: https://doi.org/10.55126/ijzab.2026.v11.i01.023

Received on: 25/10/2025

Revised on: 27/11/2025

Accepted on: 23/12/2025

Published on: 01/01/2026

  • Andal Priyadarshini A, Lochini Suriyanarayanan, Ravi Shankar P L, Sudharsana V( 2025).

    Immunological and molecular tools for the diagnosis in periodontics

    . International Journal of Zoology and Applied Biosciences, 11( 1), 180-185.

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Abstract

Periodontitis is a common immune-inflammatory oral disease. Early detection plays an important role in its prevention and progression. Saliva is a reliable medium that mirrors periodontal health and is easily obtainable for identifying periodontal biomarkers in point-of-care diagnostics. Advanced molecular and immunological diagnostic techniques are diagnostic tests utilized to detect antigen-antibody interactions and quantify nucleic acids, proteins, or metabolites in clinical samples, facilitating the identification of risk factors, screening of asymptomatic patients, enhancing diagnostic accuracy, and informing the development of optimal therapeutic interventions. The molecular and immunological diagnostic methods that might be applied to the diagnosis and treatment of periodontitis are reviewed in this paper.

Keywords

Diagnosis, Investigation, Immunology, Periodontal tissues, Saliva.

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    © The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.