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International Journal of Zoology and Applied Biosciences Research Article
Formulation and evaluation of herbal oral gel containing extracts of powdered Vitex negundo leaves with Anacyclus pyrethrum to treat mouth ulcer
Kalyani Kakad, Vikas Gore, Sneha Nawale
Year : 2025 | Volume: 10 | Issue: 5 | Pages: 1-8
Received on: 02/07/2025
Revised on: 11/07/2025
Accepted on: 29/08/2025
Published on: 30/09/2025
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Kalyani Kakad, Vikas Gore, Sneha Nawale( 2025).
Formulation and evaluation of herbal oral gel containing extracts of powdered Vitex negundo leaves with Anacyclus pyrethrum to treat mouth ulcer
. International Journal of Zoology and Applied Biosciences, 10( 5), 1-8.
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Abstract
Mouth ulcers, known as canker sores or aphthous ulcers, are common painful lesions within the oral cavity, often resulting from factors like nutritional deficiencies, stress, hormonal changes, or physical trauma. This study investigates the development of a topical gel incorporating natural therapeutic agents extracted from Vitex negundo and Anacyclus pyrethrum to alleviate symptoms associated with mouth ulcers. These botanical extracts exhibit anti-inflammatory, analgesic, and antimicrobial properties that can reduce pain and promote oral ulcer healing. The gel formulations, formulated with appropriate gelling agents and excipients, underwent evaluation based on appearance and consistency to identify the optimal formulation. The selected formulation will undergo further antimicrobial studies to assess its effectiveness in managing mouth ulcers. In conclusion, the development of a topical gel containing bioactive compounds from Vitex negundo and Anacyclus pyrethrum represents a promising approach for treating mouth ulcers. This research contributes to the understanding of natural remedies for oral health conditions and highlights the potential of botanical extracts in topical formulations for managing oral ulcers.
Keywords
Antiulcer activity, Wound healing, Gel formulation, Oral health, Evaluation.
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© The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
