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International Journal of Zoology and Applied Biosciences Research Article
Comparative effects of plant-based low-sodium salts and sodium chloride on obesity markers in Wistar rats
Ameyran Koami, Mélila Mamatchi, Feteke Lochina, Satchi Kuévi, Afangbom Kossi, Dandonougbo Koffi, Amouzou Kou’santa
Year : 2025 | Volume: 10 | Issue: 5 | Pages: 189-197
Received on: 22/07/2025
Revised on: 01/08/2025
Accepted on: 07/09/2025
Published on: 31/09/2025
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Ameyran Koami, Mélila Mamatchi, Feteke Lochina, Satchi Kuévi, Afangbom Kossi, Dandonougbo Koffi, Amouzou Kou’santa( 2025).
Comparative effects of plant-based low-sodium salts and sodium chloride on obesity markers in Wistar rats
. International Journal of Zoology and Applied Biosciences, 10( 5), 189-197.
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Abstract
This study evaluated the comparative effects of plant-derived low-sodium salts (SHOV) and sodium chloride (NaCl) on obesity-related markers in Wistar rats. Sixty rats (30 males and 30 females) were randomly assigned to ten groups and orally administered SHOV or NaCl at doses of 70 mg/kg and 210 mg/kg for 28 consecutive days. Body weight, Lee index, and visceral adiposity index were assessed throughout the study. All groups exhibited progressive weight gain with no evidence of toxicity. Rats treated with 70 mg/kg SHOV showed growth patterns similar to the control group, whereas the 210 mg/kg dose produced slightly lower weight gain, suggesting a potential moderating effect on energy metabolism. The Lee index increased moderately during the experiment but remained statistically comparable to the control under SHOV, unlike NaCl, which significantly elevated this index on days 21 and 28. Visceral adiposity was lower in SHOV-treated rats, particularly at 210 mg/kg, and higher under NaCl at 70 mg/kg (p < 0.05). A sex-dependent difference was also observed, with males exhibiting greater adiposity than females. Overall, SHOVs appear to promote improved water mineral and lipid homeostasis, thereby limiting fat accumulation and mitigating the deleterious effects of sodium. Plant-based low-sodium salts thus represent a promising nutritional alternative for the prevention of obesity and its associated metabolic complications.
Keywords
Plant-derived low-sodium salts, Sodium chloride, Obesity, Adiposity index, Wistar rats.
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© The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
