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International Journal of Zoology and Applied Biosciences Research Article

Received on: 10/11/2025

Revised on: 18/12/2025

Accepted on: 08/01/2026

Published on: 31/01/2026

  • Anand Pundlik Bothe( 2026).

    Assessment of an antimicrobial property of selected antibiotics against the selected bacterial food pathogens

    . International Journal of Zoology and Applied Biosciences, 11( 1), 273-278.

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Abstract

Foodborne bacterial pathogens are a leading cause of food-related illnesses worldwide, posing significant public health and economic challenges. The increasing prevalence of antibiotic resistance among these pathogens necessitates continuous evaluation of antimicrobial agents. The present study investigates the antimicrobial efficacy of selected antibiotics against major bacterial food pathogens, including Escherichia coli, Salmonella enterica, Staphylococcus aureus, Listeria monocytogenes, and Bacillus cereus. Antibiotics belonging to different classes ampicillin, ciprofloxacin, tetracycline, chloramphenicol, and gentamicin—were assessed using agar disc diffusion, agar well diffusion, and minimum inhibitory concentration (MIC) assays. The results demonstrated differential susceptibility patterns among the tested pathogens. Ciprofloxacin and gentamicin exhibited the highest antimicrobial activity, while reduced sensitivity and resistance were observed against ampicillin and tetracycline, particularly in Gram-negative bacteria. Gram-positive pathogens showed comparatively higher susceptibility to most antibiotics. The observed resistance trends highlight the potential risks associated with the indiscriminate use of antibiotics in food production systems. This study emphasizes the importance of routine antimicrobial surveillance and rational antibiotic use to ensure food safety and mitigate the spread of resistant foodborne pathogens.

Keywords

Foodborne bacteria, Antibiotics, Antimicrobial activity, MIC, Antibiotic resistance, Food safety.

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    © The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.