SUBMIT MENUSCRIPT TRACK YOUR ARTICLE

Latest News

  • Submission of Papers: Authors are requested to submit their papers electronically through the website Login (Submit Manuscript). If you are unable to submit your paper through online submission, kindly send it to [email protected]

  • Reprint & Publication Certificate: After Publication, every author will receive a soft copy of the Reprint and Publication Certificate will be sent to the requested author.
  • Author Guidelines: Authors are requested to follow the Author Guidelines (https://www.ijzab.com/author/) for the manuscript preparation.
  • UGC-CARE list: Our journal was already in the UGC approved list (Sl. No. 3116, Journal No. 46511), but our journal is not in the revised UGC-CARE list. We are trying to fulfill the required criteria to include in the UGC-CARE list.
  • Call for Paper: Authors are requested to submit Research Articles for the publication in the International Journal of Zoology and Applied Biosciences for the current/forthcoming issue.

  • The National Academy of Agricultural Sciences (NAAS rated Journal)

Archives


International Journal of Zoology and Applied Biosciences Research Article

Arsenic and its mitochondrial toxicity: A review

A. Arunachalam, N. Nanthini, S. Malathi and A. Ragapriya

Year : 2017 | Volume: 2 | Issue: 4 | Pages: 195-201

doi: https://doi.org/10.5281/zenodo.1311974

Received on: 07/10/2017

Revised on: 08/13/2017

Accepted on: 08/14/2017

Published on: 08/31/2017

  • A. Arunachalam, N. Nanthini, S. Malathi and A. Ragapriya( 2017).

    Arsenic and its mitochondrial toxicity: A review

    . International Journal of Zoology and Applied Biosciences, 2( 4), 195-201.

  • click to view the cite format


Abstract

The present review article deals with environmental origin of arsenic (As) and its oxidative stress mediated mitochondrial toxicity of arsenic. It is a metalloid compound occurs naturally, being the 20th most abundant element in the earth’s crust, and is a component of more than 245 minerals. The presence of As in the environment may be due to both natural and anthropogenic sources. The symptoms of As toxicity either through consumption of contaminated ground water or food crops. The toxicity of As compounds depends on a number of factors. Mostly inorganic trivalent form of Asarsenite (AsIII) is more toxic than arsenate (AsV). Reactive oxygen species (ROS)-mediated oxidative damage is a common denominator in As pathogenesis. In addition, arsenic induces morphological and molecular changes in the integrity of mitochondria through ROS mediated oxidative stress. Further the mechanisms of free radical formation derived from the superoxide radical, combined with glutathione-depleting agents, increase the sensitivity of cells to arsenic toxicity because of its sulfhydryl groups (SH). Finally this review article included origin of ‘As’ and oxidative stress mediated mitochondrial toxicity to address the ‘As’ induced mechanism of mitochondrial dysfunction.

Keywords

Arsenic, Toxicity, Ground water, Mitochondria, Oxidative stress.

  • Full Article PDF ( 2238)

  • View HTML Article

    • Copy Rights

    © The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

SiteLock

Copyright © 2026 Rishan Publications. All Rights Reserved. Slot Site

powerdby
0