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International Journal of Zoology and Applied Biosciences Research Article
Analytical and bioanalytical perspectives on doxazosin for biosciences and therapeutic research
Vara Prasada Rao K, Sai Sri Harshitha N, Usha Rani S, Nithya Sri D, Devika Rani Ratnanjali A, Paridhi J and Sumaiah Banu SK
Year : 2025 | Pages: 354-363
Received on: 10/09/2025
Revised on: 21/10/2025
Accepted on: 14/11/2025
Published on: 30/11/2025
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Vara Prasada Rao K, Sai Sri Harshitha N, Usha Rani S, Nithya Sri D, Devika Rani Ratnanjali A, Paridhi J and Sumaiah Banu SK( 2025).
Analytical and bioanalytical perspectives on doxazosin for biosciences and therapeutic research
. International Journal of Zoology and Applied Biosciences, 10( 6), 354-363.
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Abstract
Doxazosin, a selective antagonist of alpha-1 adrenergic receptor which is commonly applied for curing hypertension and benign prostatic hyperplasia. For pharmaceutical quality control and efficient treatment monitoring, doxazosin estimation in biological fluids must be done precisely. Numerous analytical and bioanalytical techniques developed for its detection are integrated in this comprehensive study, including spectrophotometric techniques, electrophoretic approaches, and chromatographic techniques (HPLC, UPLC, and LC-MS/MS). In the current study overview of doxazocin and its pharmaceutical significance along with physicochemical properties, analytical and bioanalytical methods, recent developments that improve analytical performance, bioanalytical method validation, various validation parameters are highlighted. This review provides a comparative evaluation of different methods, emphasising their benefits, drawbacks, and suitability for use in various academic, professional and industrial contexts.
Keywords
Doxazosin, Benign prostatic hyperplasia, Hypertension, Spectrophotometric techniques, Evaluation.
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© The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
