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International Journal of Zoology and Applied Biosciences Research Article
An overview on fabrication, pharmaceutical properties, characterization and applications of pharmaceutical cocrystals
Venkata Deepthi Vemuri, Sravani Boyapati, Sasikala Allam, Karimajji Madhavi, Gurijala Lekhya
Year : 2025 | Pages: 302-313
Received on: 07/09/2025
Revised on: 19/10/2025
Accepted on: 10/11/2025
Published on: 30/11/2025
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Venkata Deepthi Vemuri, Sravani Boyapati, Sasikala Allam, Karimajji Madhavi, Gurijala Lekhya( 2025).
An overview on fabrication, pharmaceutical properties, characterization and applications of pharmaceutical cocrystals
. International Journal of Zoology and Applied Biosciences, 10( 6), 302-313.
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Abstract
Cocrystals are the idea of supramolecular chemistry to what end they are obtaining the substantial attentiveness of researchers belonging to chemical and pharmaceutical science and the medicament regulatory agencies. Although, these cocrystals set up their site in pharmaceuticals, mainly because of their capacity to change the physicochemical effects without understanding the constitutional coherence of API and consequently, maybe, the bioactivity. This article is deliberated to merge literature working on cocrystallization, a gadget for increasing solubility and for developing the properties of active pharmaceutical ingredients with exceptional significance on the mechanism behind it. Although, the formation of pharmaceutical cocrystals can be challenging, consequently decreasing the translation into feasible drug by-products. This review additionally furnishes a short introduction to the cocrystals nature. These pharmaceutical cocrystals are appearing as a new category of solid drugs with the upgraded physicochemical effects, to what end fascinated improved interests belonging to both academic and industrial researchers. The properties of different drugs had been accessible on the pharmaceutical market for an old-time required to be upgraded. The impact of choosing suitable preparation and design on these challenges has been discussed. Cocrystallization is an appearing proceed towards to increase dissolution profile, solubility, bioavailability, and some other mechanical and physicochemical effects of an active pharmaceutical ingredient Cocrystals the collection of active pharmaceutical ingredients and pharmaceutically tolerable coformer.
Keywords
Cocrystals, Coformers, Polymorphs, Dissolution, Solubility.
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© The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
