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International Journal of Zoology and Applied Biosciences Research Article
Evaluating the therapeutic efficacy of two culinary mushrooms: a comparative study on the antioxidant and anticancer activities of Pleurotus eryngi and Hypsizygus marmoreus
Parvathi K O, Jini Joseph, Rose Mary and Jesly Jose
Year : 2026 | Volume: 11 | Issue: 2 | Pages: 9-18
Received on: 03/01/2026
Revised on: 20/01/2026
Accepted on: 07/02/2026
Published on: 01/03/2026
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Parvathi K O, Jini Joseph, Rose Mary and Jesly Jose( 2026).
Evaluating the therapeutic efficacy of two culinary mushrooms: a comparative study on the antioxidant and anticancer activities of Pleurotus eryngi and Hypsizygus marmoreus
. International Journal of Zoology and Applied Biosciences, 11( 2), 9-18.
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Abstract
The present study was conducted to assess the phytochemical profile, antioxidant activity and anticancer activity of the most widely consumed culinary mushrooms Pleurotus eryngi and Hypsizygus marmoreus. Molecular identification of the species has been done by sanger sequencing technique. Qualitative analysis authenticated the presence of necessary phytochemicals including glycosides, phenolics, alkaloids, terpenoids. The ethanolic extract of the mushrooms exhibited significant antioxidant activity in a concentration dependend manner as observed from DPPH, ABTS, FRAP and NO radical scavenging assays. Anticancer efficiency of the samples was tested using MTT assay on MCF -7 cell line. The extract produced cell cytotoxicity in a dose-dependent pattern within biologically safe levels, indicating its potential application as a cancer-preventive agent or in complementary therapy.
Keywords
Hypsizygus marmoreus, Pleurotus eryngi, Antioxidant activity, Cytotoxicity, Phytochemicals.
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© The Author(s) 2025. This article is published by International Journal of Zoology and Applied Biosciences under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
