Abstract

Pesticides are used in agriculture for centuries for eradication of unwanted insects and controlling disease vectors. The term pesticide encompasses a group of chemical compounds used to eliminate or control of pests. These pesticides through the process of biomagnification increase their concentration at the top trophic level of the food chain, including the in humans. Gambusia affinis was subjected to sub lethal concentrations of cyfluthrin and fenvalerate from 24 to 96 hours Acetylcholinesterase enzyme involved in the maintenance of the structural and functional integrity of cellular membranes. For normal behaviour and muscular function AChE activity is vital. In the present investigation there is marked decrease in AChE activity in the gill, liver, kidney and brain   tissues is observed, when the fish Gambusia affinis is exposed to the cyflthrin and fenvalerate. The intensity of inhibition of AChE activity might also correlated with the degree of accumulation of pesticide and their metabolite in different organs.

Keywords

Pesticides, Acetylcholinesterase enzyme, Decrease, tissues, Gambusia affinis.

Received on 24/06/2019, Accepted on 28/07/2019, Published on 30/07/2019