Abstract

Zebrafish has been a prominent model vertebrate in a variety of biological discipline. Sustainable information gathered from developmental and genetic research, together with mear completion of the zebrafish genome project, has placed zebrafish in an attractive position for use as a toxicological model. There is a clear potential for Branchydanio rerio to provide valuable new sights into chemical toxicity, drug discovery and human diseases using recent advances in forward and reverse genetic techniques. The present study was carried out the impact on exposure of sub lethal concentration of triclosan induced biochemical parameters. This experiment was carried out from 7th day to 28th days of the exposure of triclosan, triclosan with garlic extract, triclosan with vitamin C, garlic extract, vitamin C and maintained with control. Triclosan of 0.32g, 1ml of garlic extract and 1g of vitamin C were used in this study. The result proved that garlic extract and vitamin C were played a productive role in treated with triclosan of zebrafish and also enhances the biochemical and enzymological parameters, and it act as detoxifying agent of triclosan. This study shows the changes in biochemical parameters of blood, which has been recovering by garlic extract and vitamin C against triclosan exposed zebrafish.

Keywords

Zebrafish, Triclosan, Vitamin C, Biochemical, Garlic extract.

Received on 04/11/2017, Accepted on 14/11/2017, Published on 21/11/2017