Archives
International Journal of Zoology and Applied Biosciences Research Article
In vitro studies on the protective effect of Vitamin C against malathion induced toxicity in the goat (Capra hircus) oviduct
Geetanjli sahni and Soniya sharma
Year : 2018 | Volume: 3 | Issue: 2 | Pages: 163-167
Received on: 02/25/2018
Revised on: 03/21/2018
Accepted on: 03/23/2018
Published on: 04/10/2018
-
Geetanjli sahni and Soniya sharma( 2018).
In vitro studies on the protective effect of Vitamin C against malathion induced toxicity in the goat (Capra hircus) oviduct
. International Journal of Zoology and Applied Biosciences, 3( 2), 163-167.
-
click to view the cite format
Abstract
During the present investigations protective effect of vitamin C on Malathion induced toxicity has been analysed in ampulla region of goat. In vitro cultured oviduct tissue treated with two doses of Malathion concentration (1nm, 100 nm) shows a significant disruption of mucosa and submucosal layers, damage of mucosal folds, degeneration of microvilli, blebbing in mucosa and increase in the width of lumen of oviduct. In contrast, supplementation with Vitamin C reduces oviduct damage by Malathion. The importance of carrying out in vitro reproductive toxicology assays lies on the need of knowing alteration which these insecticides may cause at cellular level, since they are endocrine disruptors that interfere with reproductive function.
Keywords
Ampulla, Malathion, Vitamin C, Reproductive toxicity.
